AI for Sensing and Diagnosis

About the Core

The mission of the Artificial Intelligence (AI) for Sensing and Diagnosis Core is to bring together researchers with expertise in unambiguous single-molecule identification techniques, data sets of human plasma samples, and researchers in data-efficient AI algorithms to develop medical diagnostic tools such as metabolomics-based therapeutic drug monitoring device for ICU patients.

The AI for Sensing and Diagnosis Core’s responsibilities include: 1) Establishment of initial workflow to support data generation and analysis; 2) Demonstrate the application of Al for optimizing medical outcomes; 3) Contributing to the BDHSC’s efforts to assess, catalogue, and advance the healthcare-related data sets available to UofSC researchers; 4) Conducting education and outreach activities to connect infrastructure, data, analytic tools and data scientists and researchers

The AI for Sensing and Diagnosis Core is co-directed by Drs. Qian Wang (CAS) and Chris Sutton (CAS) and consists of strong expertise in biomaterials, nanomaterials, drug discovery, biosensing, and biosensor development. Please contact Dr. Wang at wang263@mailbox.sc.edu or Dr. Sutton at cs113@mailbox.sc.edu.

Activity 1

The AI for Sensing and Diagnosis Core aims to foster the collaborative research activities in the forefront of biomaterials and nanomaterials sciences. Some ongoing research projects include: using the big data approach to develop bionanopore-based de novo protein/peptide sequencing techniques for clinical point-of-care applications; developing automation method to investigate cellular responses to different nanomaterials; nanomaterial catalyst for clean and environmental-friendly energy conversion and storage; and developing a rationale design platform for disease-modifying nanoparticles.

Activity 2

Investigators of the Ai for Sensing and Diagnosis Core have diverse content expertise in the area of nanomaterials and biomaterials research. We offer our assistance and consultation and potential collaboration to your research project or grant, or business development.

Activity 3

The Ai for Sensing and Diagnosis Core hosts a variety of seminars, courses, and workshops on bio/nanomaterials sciences for investigators and students across a broad range of disciplines. Please check the Events tab for more information and future event dates. You can also contact our Directors for course-related listings offered on the UofSC campus.

Faculty

Qian Wang, Ph.D.

Core Co-Lead

The research in Wang group is divided into four distinctive but inter-connected topics: (1) chemoselective functionalization of bionanoparticles (BNPs); (2) self-assembly of BNPs towards materials development; (3) cell-recognition study with BNP-assemblies; and (4) fluorogenic reaction for protein imaging and recognition. All these researches point to one direction: to build three-dimensional programmable scaffolds that mimic the native extracellular matrices and can be used to probe the cellular activities.

Chris Sutton, Ph.D.

Core Co-Lead

Dr. Sutton’s research is focused on developing and applying computational approaches such as density functional theory combined with machine-learning methods to design, predict, and understand new and functional materials. He is an assistant professor in the Department of Chemistry and Biochemistry. 

Dr. Banister is a Clinical Assistant Professor in the Department of Drug Discovery and Biomedical Sciences at the College of Pharmacy. 

Dr. Chen’s research interests include synthesis and characterization of materials for energy conversion and storage, catalysis and electrocatalysis, composition, structure & property relationship, ionic and electronic conducting ceramics, solid oxide fuel cells, solid oxide electrolysis cells, and gas separation membranes.

Ming Hu, Ph.D.

Core Member

Dr. Hu’s research interests include modeling and simulation of micro-/nano-scale thermal transport in novel energy systems, in particular low-dimensional materials and nanostructures, and energy nanotechnology, interfacial heat transfer for advanced thermal management, and multi-scale and multiphysics modeling of complex energy transport process.

Dr. Lessner’s research interests center on the vascular biology and biomechanics of atherosclerosis, with an emphasis on intraplaque angiogenesis (new blood vessel growth) and mechanical failure (plaque rupture). Atherosclerotic plaque rupture is a leading cause of acute cardiovascular events such as heart attack and stroke. Evidence available to date suggests that plaque rupture results from an adverse interaction between biomechanical and biological factors. 

Chang Liu, Ph.D.

Core Member

Dr. Liu is an Assistant Professor in the Department of Chemical Engineering, Biomedical Engineering at the College of Engineering and Computing. His projects include Point-of-care diagnostics for resource-limited settings, Translational biomarkers and biosensors to enable personalized medicine, and Nanostructure-based tools for fundamental biochemical studies.